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Two members of our lab, Nidhi Singh and Osayamen Obanor, had the exciting opportunity to present their research at ASM Microbe 2025 in Los Angeles. They shared their work through poster presentations and rapid fire talks at the Antimicrobial Agents and Resistance (AAR) track hub.

Bulman Lab Members at ASM Microbe

Dr. Xing Tan, an Infectious Diseases Pharmacy Fellow, helped the Bulman Lab develop a novel PK/PD biofilm model, which was published in NPJ Biofilms and Microbiomes, a nature journal. The optimized in vitro air-liquid interface pharmacokinetic/pharmacodynamic biofilm model may be beneficial for the development of novel anti-biofilm agents or to optimize antibiotic dosing for infections such as ventilator associated bacterial pneumonia. It also helps show the benefits of using inhaled antibiotics against bacterial biofilms, which may be present in the lungs. The article can be read here.

Tan et al. NPJ Biofilms and Microbiomes

Dr. Bulman, in collaboration with leaders from 3 international infectious disease societies, led the development of a personal view article published in Lancet Microbe that sought to emphasize several key research priorities in antibiotic PK/PD. Although progress has been made in our quest to optimize the treatment of infections, additional research will be required to fully realize the potential of precision antibiotic therapy and its ability to improve patient outcomes. The article was also featured on ContagionLive.

Bulman et al. Lancet Microbe

Dr. Zackery Bulman recently received a $3.66 million, 5-year R01 grant as PI for his project titled, “Precise Combination Strategies Targeting Carbapenem-Resistant Klebsiella pneumoniae” (R01AI173064). This R01 is the largest R01 in the history of the UIC College of Pharmacy (based on NIH Reporter data). This project will develop new antibiotic combination treatment approaches for drug-resistant superbugs, which can cause serious infections associated with high mortality rates.

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